F. The trial’s intervention of interest (right and/or left lateral position) involves comparison with ≥ 1 of the following body positions Opposite lateral position, supine position, semi Fowler’s or semi recumbent position, Fowler’s position, high Fowler’s position, prone position, reverse Trendelenburg position or Trendelenburg position (see instructions) With regards to the intervention of interest (the lateral position) and comparisons 2. Each body position should be maintained for ≥ 10 minutes before the next position change to be eligible for inclusion. Kinetic therapy and continuous lateral rotation therapy (CLRT) may be eligible, if separate data are provided for right and left lateral position with duration ≥ 10 minutes in each position
Yes 1 2 (circle number)	No 1 2 (circle number)	Unclear 1 2 (circle number)
G. The trial reports ≥ 1 of the following outcome measures In‐hospital mortality Incidence of morbidity (pulmonary, cardiovascular and other) Clinical adverse events (i.e. hypoxaemia, cardiac arrhythmias, hypertension, hypotension, indicators of haemodynamic compromise (i.e. alternations in oxygen delivery determinants or global indices of tissue oxygenation)) Pulmonary physiology (oxygenation and pulmonary artery pressures) oxygenation measured by oxygenation index (OI) (mean airway pressure × FiO2 × 100/PaO2) and hypoxia score (PaO2/FiO2 ratio) Vital signs (respiratory rate, heart rate, blood pressure, temperature) Duration of mechanical ventilation Length of stay in critical care area Length of stay in hospital Any measure of patient comfort or satisfaction
Yes 1 2 3 4 5 6 7 8 9 (circle number)	No	Unclear 1 2 3 4 5 6 7 8 9 (circle number)