Supine position compared with good lung down for critically ill adult patients with unilateral lung disease
Patient or population: critically ill adult patients with unilateral lung disease Settings: critical care areas Intervention: supine position Comparison: good lung down
Outcomes	Illustrative comparative risks* (95% CI)		Relative effect (95% CI)	Number of participants (studies)	Quality of the evidence (GRADE)	Comments
	Assumed risk	Corresponding risk
	Good lung down	Supine position
Hypoxaemia Partial pressure of arterial oxygen (PaO2) ‐ not reported	See comment	See comment	‐	30 (1 studya)	See comment	Single cross‐over study, whole sample data not available.
Global indicator of alteration in tissue oxygenation Arterial‐venous oxygen content difference (C(a‐v)O2) ‐ not reported	See comment	See comment	‐	30 (1 studya)	See comment	Single cross‐over study, whole sample data not available.
*The basis for the assumed risk (e.g. median control group risk across studies) is provided in footnotes. The corresponding risk (and its 95% confidence interval) is based on the assumed risk in the comparison group and the relative effect of the intervention (and its 95% CI) CI: confidence interval
GRADE Working Group grades of evidence High quality: Further research is very unlikely to change our confidence in the estimate of effect Moderate quality: Further research is likely to have an important impact on our confidence in the estimate of effect and may change the estimate Low quality: Further research is very likely to have an important impact on our confidence in the estimate of effect and is likely to change the estimate Very low quality: We are very uncertain about the estimate
Footnote: aCross‐over trial with participants as their own controls