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. 2015 Oct 8;2015(10):CD004433. doi: 10.1002/14651858.CD004433.pub3

Azab 2009.

Methods Randomisation details were not reported
Blinded outcome assessor
No withdrawals
Single centre, outpatients
Participants Jordan
Recruited from King Abudallah University Hospital
37 participants: 20 intervention, 17 control
Inclusion criteria: ability to voluntarily extend fingers and wrist slightly
Exclusion criteria: severe cognitive disabilities
Mean age (SD): 56 (9.9) years for all participants
% women: 24% of all participants
Stroke details: only ischaemic, 57% with right hemiparesis
Time since stroke, mean (SD): 2.75 (0.7) months for all participants
Interventions mCIMT versus control
mCIMT: active range of motion of bilateral upper extremities, stretching exercises, hand‐eye co‐ordination activities, ambulation, and strengthening exercises for bilateral upper extremities
Amount of restraint: 6 to 7 hours per day
Anatomical region restraint: hand
Control: active range of motion of bilateral upper extremities, stretching exercises, hand‐eye co‐ordination activities, ambulation, and strengthening exercises for bilateral upper extremities
Session duration: 4 hours per week (in 3 day/week) for 4 weeks for both groups
Outcomes Measures pre/post treatment and follow‐up at 6 months
  • ADL measure: BI

Notes  
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) High risk Information provided only in the abstract
Quote: "Key words: Barthel Index, CIMT, stroke randomized control study"
Allocation concealment (selection bias) Unclear risk No information provided
Blinding (performance bias and detection bias) 
 All outcomes Low risk Quote: "The occupational therapist and the two physical therapists were double‐blinded to the therapy and group assignment of the patients"
Incomplete outcome data addressed? (Post‐treatment) Unclear risk Quote: "The BI was measured at the beginning of the rehabilitation program and at the discharge from rehabilitation. The BI was also re‐evaluated at 6 months post discharge in 18 patients (64% of the initial experimental group)"