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. 2015 Oct 8;2015(10):CD004433. doi: 10.1002/14651858.CD004433.pub3

Lin 2010.

Methods Randomisation details were not reported
 Blinding of outcome assessor not reported
 No information about withdrawals
 Multicentre, outpatients
Participants Taiwan
Recruited from 2 medical centres
13 participants: 5 intervention, 8 control
Inclusion criteria: cerebrovascular accident > 3 months; ability to extend actively at least 20° at the wrist and 10° at the metacarpophalangeal and interphalangeal joints on the last 4 fingers of the affected hand; sufficient cognitive ability
Exclusion criteria: not reported
Mean age (SD): intervention group: 46.04 (26) years, control group: 51.06 (12.4) years
 % women: intervention group 40%, control group: 0%
Stroke details: ischaemic or haemorrhagic; 20% with right hemiparesis in treatment group, 62% with right hemiparesis in control group
Time since stroke, mean (SD): intervention group 21.5 (12.3) months, control group 16.3 (18.3) months
Interventions mCIMT versus control
mCIMT: functional tasks delivered through shaping approach
Amount of restraint: 6 hours per day
Anatomical region restraint: hand
Control: neurodevelopmental treatments focusing on balance training, stretching and weight‐bearing with the affected limb, fine‐motor tasks and practice of compensatory activities of daily living
Session duration: 2 hours per day, 5 days per week, 3 weeks for each group
Outcomes Measures pre/post treatment
  • Arm motor impairment: FMA

  • Perceived arm motor function: MAL

  • Functional magnetic resonance (fMRI) measures

Notes  
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Unclear risk Quote: "Participants were randomized to the dCIT [distributed Constraint‐induced therapy] or the CI [control intervention] group"
Allocation concealment (selection bias) Unclear risk Information not provided
Blinding (performance bias and detection bias) 
 All outcomes Unclear risk Information not provided
Incomplete outcome data addressed? (Post‐treatment) Unclear risk Information not provided