Table 1. Association between GAS5 polymorphisms and CRC risk.
| Genotype | Case2 | Control2 | P | Adjusted OR (95% CI)1 | ||
|---|---|---|---|---|---|---|
| n | % | N | % | |||
| rs55829688 | ||||||
| CC | 81 | 7.7 | 130 | 11.4 | 0.0066 | |
| CT | 460 | 43.5 | 500 | 43.9 | 1.50 (1.10–2.03) | |
| TT | 516 | 48.8 | 509 | 44.7 | 1.64 (1.21–2.22) | |
| CT/TT | 976 | 92.3 | 1009 | 88.6 | 1.57 (1.17–2.10) | |
| T allele | 0.6953 | 0.6919 | 0.0062 | |||
| HWE | 0.3752 | 0.5921 | ||||
| P trend | 0.0016 | |||||
| rs1951625 | ||||||
| CC | 490 | 45.5 | 524 | 44.6 | 0.8853 | |
| CT | 468 | 43.4 | 514 | 43.7 | 0.97 (0.82–1.16) | |
| TT | 120 | 11.1 | 137 | 11.7 | 0.94 (0.71–1.23) | |
| T allele | 0.3284 | 0.3353 | 0.6215 | |||
| HWE | 0.6044 | 0.5226 | ||||
| P trend | 0.6245 | |||||
1
Adjusted for age and gender in the logistic regression model.
2
The mismatch between the number of genotyping samples and a total of samples is due to the absence of samples.