Table 1.
Metabolite sums and ratios calculated with amounts accurately determined and listed according to their P-value (from the smallest to the largest).
| Ratio or sum | Fold Change (SiOPA1/ SiLUC) | Observed p-value | Corrected alpha threshold |
|---|---|---|---|
| UFA/SFA aa | 0.68 | 0.00021 | 0.0089 |
| UFA/SFA ae | 0.83 | 0.00209 | 0.0132 |
| SFA ae | 1.66 | 0,02323 | 0.0170 |
| SFA aa | 1.66 | 0.02881 | 0.0204 |
| Putrescine/Spermidine | 1.23 | 0.05381 | 0.0236 |
| Spermine/Spermidine | 1.51 | 0.15641 | 0.0266 |
| Methionine-SO/Methionine | 1,14 | 0.19032 | 0.0294 |
| Citrulline/Arginine | 0.27 | 0.19280 | 0.0321 |
| MUFA ae | 1.27 | 0.24745 | 0.0348 |
| PUFA ae | 1.20 | 0.24745 | 0.0374 |
| Total lysoPC/ Total PC | 0.75 | 0.24745 | 0.0399 |
| MUFA aa | 1.17 | 0.31499 | 0.0423 |
| PUFA aa | 1.03 | 0.63053 | 0.0447 |
| Tyrosine/Phenylalanine | 0.97 | 0.63053 | 0.0470 |
In order to determine significance of each sum or ratio, observed p-values should be lower than the corrected alpha threshold. Legend: SFA: saturated fatty acids; MUFA: mono-unsaturated fatty acids; PUFA: poly-unsaturated fatty acids; UFA: unsaturated fatty acid, equal to the sum of MUFA and PUFA; Methionine-SO: sulfoxidized methionine; PC: phosphatidylcholine; aa: diacyl; ae: acyl-alkyl.