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. 2019 Apr 15;10:1747. doi: 10.1038/s41467-019-09743-4

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Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 4 — Quantifying side-chain motions on the millisecond timescale. CEST profiles to quantify millisecond chemical exchange of V103 ¹³C^γ2 in T4L L99A at 278 K are shown. The circles represent experimentally obtained normalised intensities, and the lines are the result of a least-squares fit. Uncertainties in the reported ϖ_G and ϖ_E are obtained using the covariance method in the least-squares fit (see Materials and Methods for full details)