Figure 4.
Non-immune IgM-binding and specific PfEMP1 expression on the surface of erythrocytes infected by P. falciparum sub-clones. Representative sub-clones generated by single-cell sorting and labeled with rat IgG specific for the PfEMP1 corresponding to the dominantly transcribed var gene (green) (A), or non-immune IgM (B). Background labeling indicated in black. Correlation (rs) of non-immune IgM-binding and labeling by PfEMP1-specific IgG for all sub-clones (C).