Table 4.
L4 (rplD) and L22 (rplV) amino acid substitutions.
| E. coli | L4 | L22 | MRG | MIC ± PAβN | |
|---|---|---|---|---|---|
| N | Y | ||||
| Commensal | V52I | I4L + L6Q + T72A | — | 16 | 0.125 |
| Commensal | A37S + V52L | wt | — | 16 | 1 |
| Commensal | wt | I4L + K6Q + T72A | — | 16 | 1 |
| Commensal | V52I + D91E + T173N | wt | — | 16 | 2 |
| Commensal | wt | S101T + I103L | — | 64 | 2 |
| DAEC | wt | K83N + D94H + K98N | mph(A) | 64 | 4 |
| EAEC | wt | V17I | — | 2 | 1 |
| EAEC | A37T + K74T | wt | — | 4 | 1 |
| EAEC | V120I | wt | — | 4 | 1 |
| EAEC | wt | L46Q | mph(A) | 64 | 16 |
| EAEC | K123S | I4L + K6Q | —a | >256 | 128 |
| EPEC | A190V | wt | msr(A) | 8 | 0.5 |
| EPEC | D154E | wt | — | 8 | 1 |
| EPEC | V52I + T173N | I4L + K6Q + T72A | mph(B) | 16 | 4 |
| EPEC | K123S | I4L + K6Q + T72A | — | 32 | 1 |
| ETEC | wt | L46Q | — | 64 | 16 |
| ETEC | wt | L46Q | — | 128 | 2 |
PAβN: Phe-Arg-β-Naphtylamyde; MRG: Macrolide resistance gene; wt: wild type. N: Absence of PAβN; Y: Presence of PAβN.
aA non-identified conjugative mechanism of resistance was detected (isolate 3491).