Figure 1.

MRI and ¹⁸F-Flortaucipir PET scans in svPPA and C9orf72-mutation carriers. Transversal and coronal slices of structural (T1-mprage) MRI scans and ¹⁸F-Flortaucipir PET scans are shown for all included subjects with semantic variant primary progressive aphasia (svPPA) and bvFTD due to a hexanucleotide expansion in the C9orf72-gene. Case numbers correspond to case numbers in Table 1. Below the individual images are mean SUVR-images of 40 AD patients and the 54 controls in MNI-space, included for comparative purposes. The images are presented in radiological orientation (left in the image corresponds to patient right). Asterisks indicate the most affected side in the svPPA cases. Scale bar for PET-scans represents standardized uptake value ratios (SUVR). An identical figure with SUVR range 0.5–3 is included as Supplementary Fig. 5.