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. 2019 Apr 15;5:89. doi: 10.1038/s41420-019-0167-5

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 8 — miR-4521 induces cell migration and invasion via TIMP-1/ MMP2/MMP9 pathways and also suppresses cell apoptosis by the MDM2/p53/Bcl2/Bax pathway by targeting FAM129A mediating ccRCC malignant behaviors. ccRCC clear cell renal cell carcinoma