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. 2019 Apr 15;9:6029. doi: 10.1038/s41598-019-42413-5

Figure 5.

Figure 5

Optogenetic stimulation of mossy fibers in the left MCP as a CS fails to support the acquisition of the TEC with a 500-ms trace interval. (a) Upper panel: the trace conditioning with a 500-ms trace interval paradigm illustrating the timing of the CS and US. Below panel: the representative O.O. EMG of the ChR2/paired, mCherry/paired, and ChR2/unpaired groups on the 18th conditioning session. (b) Average CR% for ChR2/paired, mCherry/paired and ChR2/unpaired groups (2-way ANOVA with repeated measures). (c) Individual learning curves of rats in ChR2/paired group. (df) EMG response topographies across two habituation and eighteen acquisition training sessions in the ChR2/paired (d), mCherry/paired (e), and ChR2/unpaired (f) groups. Data are represented as mean ± s.e.m.