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. 2019 Apr 15;9:6062. doi: 10.1038/s41598-019-42532-z

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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ASL image in the THC model. The figure shows anatomical (T2 weighted) images in the top part, the delineation of regions of interest for the ASL analysis (central part) and perfusion map (bottom part) in one representative animal from each CTR and THC exposed group. ROIs are numbered as follows. At +1.6 mm position from bregma: 1 – prefrontal cortex, 2 – caudate putamen; at −3.14 mm position from bregma: 3 – sensorimotor cortex, 4 – hippocampus, 5 – circle of Willis.