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. 2019 Apr;10(2):244–253. doi: 10.21037/jgo.2018.12.09

Table 3. Levels of pro- and anti-inflammatory cytokines during and after HIPEC surgery.

Cytokines t1 t2 t3 t4 t5 t6 t7
CRP (mg/mL) 7±11 6±9 8±10 17±15 55±26 113±36 154±70
IL-1RA (pg/mL) 557±2,108 1,640±3,830 4,972±3,149 4,026±3,218 3,248±2,791 487±587 271±271
IL-6 (pg/mL) 16±77 282±399 994±1,314 1,973±3,346 1,380±2,229 157±348 50±100
IL-10 (pg/mL) 9±35 70±213 58±145 47±76 101±116 31±34 10±8
IL-18 (pg/mL) 82±51 76±37 84±40 85±41 119±61 126±79 145±96
TNFα (fg/mL) 45±202 17±38 41±149 74±270 60±13 29±56 18±38
MCP-1 (pg/mL) 181±309 1,113±2,601 1,442±2,132 2,613±9,111 500±619 175±168 129±126
IL-8 (pg/mL) 17±57 161±164 356±453 395±575 187±311 25±42 9±10
Elastase (ng/mL) 80±83 129±100 169±96 181±115 199±98 150±101 142±104
C5a (ng/mL) 101±66 68±31 68±32 98±94 138±1,106 99±63 122±76

HIPEC, hyperthermic intraoperative intraperitoneal chemotherapy; CRP, C-reactive protein; MCP-1, monocyte chemotactic protein 1.