| N |
10 |
10 |
| Age [range], years |
88 [74–93] |
81 [71–89] |
| Karnofsky Performance Status (KPS) |
80 |
80 |
| Stage |
|
|
| T2N0 |
3 |
4 |
| T3N0 |
6 |
6 |
| T3N1 |
1 |
0 |
| Tumor response |
9 evaluable patients |
10 evaluable patients |
| Complete |
3—1 by colonscopy with negative biopsy (4 months), 1 by colonscopy with no lesion to sample (6 months), 1 by colonoscopy with no lesion and PET-CT (10 months) |
2 [low anterior resection (LAR)]—interval between SCRT and surgery of 3 and 8 weeks respectively |
| Partial |
4—2 by colonscopy and magnetic resonance imaging (MRI) (9 and 12 months), 1 by PET-CT (10 months), 1 by MRI (6 months) |
5 [3 abdominoperineal resection (APR), 1 LAR, 1 trans-anal endoscopic microsurgery (TEMS)]—4 with interval between <1 and 2 weeks, 1 with 35 weeks to TEMS |
| Progressive disease |
2—by imaging and clinical exam (4 and 5 months) |
– |
| No response |
– |
2 (3 LAR)—interval <1 week for all patients |
| Death from colorectal cancer |
2 |
0 |
| Surgical mortality |
– |
3 |
