Table 1.
Genetic classification of MODY subtypes
| Type | Gene | Frequency, %MODY families | Penetrance |
|---|---|---|---|
| MODY1 | HNF-4α | 2–4 | High |
| MODY2 | GCK | 11–63 | 100% |
| MODY3 | HNF-1α | 21–73 | High |
| MODY4 | IPF-1/PDX-1 | 1–4 | High |
| MODY5 | HNF-1β | 1–5 | High |
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