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. 2019 Apr 9;10:734. doi: 10.3389/fmicb.2019.00734

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Copyright © 2019 Zheng, Ding, Lou, Tong, Zhuo, Ding, Kong and Lu.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Humoral response in BALB/c mice induced by pVAX1-MYR1 immunization. (A) Total IgG, (B) IgG1, and (C) IgG2a. The total IgG and IgG subclass (IgG1 and IgG2a) titers were determined at 0, 2, 4, and 6 weeks after first vaccination. Data are expressed as the mean ± SD (n = 9) values from three independent experiments. ^∗p < 0.05, indicates a significant difference in comparison with the control groups.