Table 2.

Cytokine production and splenocyte proliferation in BALB/c mice immunized with pVAX1-MYR1.

Groups (n = 5)	Cytokine production (pg/ml)				Proliferation (SI)a
	IFN-γ	IL-12	IL-4	IL-10
Blank control	35.23 ± 3.28	29.22 ± 2.99	30.01 ± 5.13	20.34 ± 1.98	0.87 ± 0.15
PBS	38.23 ± 4.35	32.08 ± 3.19	31.29 ± 4.29	19.56 ± 2.91	0.78 ± 0.09
pVAX1	36.21 ± 3.98	35.01 ± 3.78	33.45 ± 3.68	21.55 ± 2.89	0.81 ± 0.12
pVAX1-MYR1	839.87 ± 60.39∗	405.29 ± 67.81∗	31.26 ± 3.28∗	86.81 ± 9.03∗	2.72 ± 0.28∗

^aSI stands for stimulation index. Splenocytes from mice were harvested 2 weeks after the last immunization. Data are expressed as the mean ± SD values (n = 5) from three independent experiments. ^∗p < 0.05, indicates a significant difference in comparison with the control groups.