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. 2019 Apr 9;10:644. doi: 10.3389/fimmu.2019.00644

Table 2.

Kidney transplant patient data summary.

Patient Time from transplant ANC (K/uL) Treatment (daily doses) Neutrophil response to A. fumigatus
No compound With C-016
Neutrophils recruited %Fungus alive Neutrophils recruited %Fungus alive
#1 6 months 12.24 Prograf 4 mg,
Prednisone 20 mg,
MMF 1 g
222 56.6% 1,648 2%
#2 6 years 1.93 Prograf 4.5 mg,
Prednisone 5 mg,
MMF 1 g
447 3.6% 806 0.4%
#3 14 years 4.58 Prograf 0.5 mg,
Prednisone 2.5 mg,
Cell Cept 500 mg
18 61.6% 1166 2%
#4 1 month 0.95 Prograf 6 mg,
Prednisone 15 mg,
Cell Cept 750 mg,
Cefepime,
Valcyte and Bactrim
17 55.7% 52 29.3%
#5 7 years 2.47 Prograf 3 mg,
Cell Cept 500 mg,
Prednisone 5 mg
71 43.2% 1496 5.1%
#6 3 years 9.34 Cyclosporine 125 mg,
Cell Cept 500 mg,
Prednisone 5 mg
26 53.3% 1,152 0%
Average Transplant Patients 133.5 ± 70.4 45.67 ± 8.8 1,053 ± 233.5 6.47 ± 4.6
Average Healthy Controls 194.2 ± 100 26.1 ± 5.1 1,966 ± 158.3 0.58 ± 0.2
Comparison between with and without C-0016 p = 0.012 p = 0.006