Table 1.
Most significantly impacted metabolic pathways in E. coli O26:H11 cells and S. Typhimurium ATCC 13311 when exposed to a lethal EB dose as a function of time post EB exposure.
| Comparing 0 kGy and 3 kGy exposed E. coli O26:H11 cells (0 kGy Control and EB 0 h) | Comparing 3 kGy exposed E. coli O26:H11 cells immediately after exposure and 24 h post EB exposure (EB 0 h and EB 24 h) |
|---|---|
| Pentose and glucuronate interconversions | Butanoate metabolism |
| Pantothenate and CoA biosynthesis | Nicotinate and nicotinamide metabolism |
| Starch and sucrose metabolism | Cysteine and methionine metabolism |
| Beta-alanine metabolism | Beta-Alanine metabolism |
| Alanine, aspartate, and glutamate metabolism | Alanine, aspartate and glutamate metabolism |
| Inositol phosphate metabolism | Citrate cycle (TCA cycle) |
| Comparing 0 kGy and 2 kGy S. Typhimurium ATCC 13311 exposed cells (0 kGy Control and EB 0 h) | Comparing 2 kGy exposed S. Typhimurium ATCC 13311 cells immediately after exposure and 24 h post EB exposure (EB 0 h and EB 24 h) |
| Propanoate metabolism | Propanoate metabolism |
| Tryptophan metabolism | Phenylalanine, tyrosine and tryptophan biosynthesis |
| Beta-Alanine metabolism | Beta-Alanine metabolism |
| Inositol phosphate metabolism | Cysteine and methionine metabolism |
| Alanine, aspartate, and glutamate metabolism | Alanine, aspartate, and glutamate metabolism |
| Butanoate metabolism | |
| Nicotinate and nicotinamide metabolism | |
| Glycerolipid metabolism | |
| Benzoate degradation via CoA ligation | |
| Arginine and proline metabolism | |
| Phenylalanine metabolism | |
| Tyrosine metabolism | |
| Pantothenate and CoA biosynthesis | |
| Aminoacyl–tRNA biosynthesis | |
| Glyoxalate and dicarboxylate metabolism | |