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. 2019 Apr 9;9:231. doi: 10.3389/fonc.2019.00231

Table 1.

Association of CD68, CD163, CCL2, CCR2 expression with clinicopathological parameters of SACC patients.

Variables n CD68 expression P-value CD163 expression P-value CCL2 expression P-value CCR2 expression P-value
low high low high low high low high
GENDER
Male 36 16 20 0.410 17 19 0.284 15 21 0.887 18 18 0.549
Female 35 19 16 21 14 14 21 15 20
AGE
>50 41 19 22 0.563 21 20 0.652 17 24 0.902 17 24 0.325
≤50 30 16 14 17 13 12 18 16 14
SITE
Majaor 29 12 17 0.271 13 16 0.226 11 18 0.680 15 14 0.465
Minor 42 23 19 25 17 18 24 18 24
HISTOTYPE
C/T 53 28 25 0.310 28 25 0.842 24 29 0.195 26 27 0.458
S 18 7 11 10 8 5 13 7 11
STAGE
I+II 41 27 14 0.001* 27 14 0.016* 22 19 0.011* 24 17 0.018*
III+IV 30 8 22 11 19 7 23 9 21
PERINEURAL INVASION
Negative 46 27 19 0.033* 30 16 0.008* 23 23 0.035* 26 20 0.022*
Positive 25 8 17 8 17 6 19 7 18
METASTASIS
Negative 49 29 20 0.014* 32 17 0.003* 24 25 0.039* 26 23 0.099
Positive 22 6 16 6 16 5 17 7 15

T, tubular type; C, cribriform type; S, solid type.

*

P < 0.05 by Spearman correlation test.