Fig. 2.

Flowchart of patient selection for the Meta VCI Map pilot study. Patient selection is shown for each cohort separately. Cohorts could join at any given step of image processing. The processing steps—congruent with the pipeline shown in Fig. 1—are shown at the top. Availability of clinical data was a prerequisite to be considered. The blue boxes indicate at what stage the cohort entered the pipeline, and what kind of imaging data was provided. Note that spatial normalization passed visual quality control in all cases, though (minor) manual adjustments were made in 177 (38%) cases.