Table 3.
Antimicrobial susceptibilities profiles of four parental S. Enteritidis strains and their resistant and highly resistant ciprofloxacin mutants.
| FQ Susceptibility groups | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Strain IDs | Susceptible |
Resistant |
Highly resistant |
|||||||||
| A-5 | A-7 | A-21 | A-33 | A-5 | A-7 | A-21 | A-33 | A-5 | A-7 | A-21 | A-33 | |
| No change of MIC (μg/mL) | ||||||||||||
| Amoxicillin/ Clavulanic acid | <1/0.5 | <1/0.5 | <1/0.5 | <1/0.5 | <1/0.5 | <1/0.5 | <1/0.5 | <1/0.5 | <1/0.5 | <1/0.5 | <1/0.5 | <1/0.5 |
| Ampicillin | <1 | <1 | <1 | <1 | <1 | <1 | <1 | <1 | <1 | <1 | <1 | <1 |
| Slight change of MIC | ||||||||||||
| Ceftriaxone | <0.25 | <0.25 | <0.25 | <0.25 | 0.5 | 1 | 0.5 | 1 | 0.5 | 1 | 1 | 1 |
| Gentamicin | 2 | 2 | 1 | 4 | 4 | 2 | 1 | 2 | 4 | 1 | 4 | 2 |
| Variable change of MIC | ||||||||||||
| Tetracycline | <4 | <4 | <4 | <4 | <4 | 8 | <4 | 8 | <4 | 32 | 8 | <4 |
| Streptomycin | 64 | 64 | 64 | >64 | >64 | >64 | 64 | >64 | >64 | >64 | 64 | >64 |
| Increase of MIC (Cross-resistance) | ||||||||||||
| Amikacin | 8 | 32 | 8 | 16 | 32 | >64 | >64 | >64 | >64 | >64 | >64 | >64 |
| Azithromycin | 0.12 | 0.25 | 0.12 | 0.25 | 4 | 8 | 8 | 8 | 8 | >16 | >16 | >16 |
| Chloramphenicol | 4 | 8 | 4 | 4 | 8 | 32 | 16 | 32 | 32 | >32 | >32 | 32 |
| Cefoxitin | 2 | 4 | 1 | 2 | 8 | >32 | >32 | >32 | 32 | >32 | >32 | >32 |
| Ceftiofur | 1 | 1 | 1 | 1 | 2 | 8 | 4 | 8 | 4 | 8 | 8 | 8 |