Table 7.
BD interaction analysis
| MtSNP |
Nuclear SNP |
Association results BD risk |
||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| rsID#/HGVS | gene | MA | MAF | SNP | Chr: BP | gene | MA | MAF | 2 dfp | interactionp | ORa | ORb |
| rs3088309 | ||||||||||||
| m.15452C>A | CYTB | A | 0.21 | rs1880924 | 7:141717225 | MGAM | A | 0.14 | 8.2E-08 | 1.4E-04 | 1.27 | 3.42 |
| rs12733666 | 1: 77927820 | AK5 | C | 0.18 | 2.9E-06 | 7.1E-07 | 1.14 | 0.38 | ||||
| rs7782502 | 7: 105695500 | CDHR3 | G | 0.40 | 6.6E-06 | 3.6E-05 | 0.72 | 1.45 | ||||
In presence of a major mtSNP allele, the odds ratio for adding one copy of nSNP minor allele based on interaction analysis.
In presence of a minor mtSNP allele, the odds ratio for adding one copy of nSNP minor allele based on interaction analysis.