Table 4.
Joint effects of age and body fat distribution pattern on renal function impairment in men and women
| Group/type | Patients, | Renal function | OR (95% CI) |
|
|---|---|---|---|---|
| n | impairment, n (%) | model 1 | model 2 | |
| Men <45 years of age | ||||
| Non-obese | 5,197 | 127 (2.4) | Reference | Reference |
| Peripheral obese | 620 | 20 (3.2) | 1.33 (0.82–2.15) | 0.86 (0.51–1.46) |
| Central obese | 2,906 | 170 (5.8) | 2.48 (1.96–3.14)* | 1.04 (0.79–1.36) |
| Men ≥45 years of age | ||||
| Non-obese | 3,423 | 175 (5.1) | Reference | Reference |
| Peripheral obese | 39 | 2 (5.1) | 1.00 (0.24–4.20) | 0.80 (0.18–3.62) |
| Central obese | 2,344 | 237 (10.1) | 2.09 (1.70–2.56)* | 1.42 (1.14–1.78)* |
| Women <45 years of age | ||||
| Non-obese | 2,446 | 74 (3.0) | Reference | Reference |
| Peripheral obese | 3,465 | 121 (3.5) | 1.16 (0.86–1.56) | 0.93 (0.68–1.28) |
| Central obese | 72a | 13 (18.1) | 7.06 (3.71–13.44)* | 3.14 (1.52–6.49)* |
| Women ≥45 years of age | ||||
| Non-obese | 742 | 36 (4.9) | Reference | Reference |
| Peripheral obese | 3,378 | 266 (7.9) | 1.68 (1.17–2.40)* | 1.06 (0.73–1.55) |
| Central obese | 458 | 93 (20.3) | 5.00 (3.33–7.49)* | 2.04 (1.31–3.16)* |
Model definitions are: model 1, unadjusted analysis; model 2, adjusted for mean arterial pressure, fasting glucose and hsCRP level, fasting glucose, total cholesterol, triglycerides, LDL-C, HDL-C and TG/HDL-C. OR, odds ratio; CI, confidence interval; hsCRP, high-sensitivity C-reactive protein; LDL, low-density lipoprotein; HDL, high-density lipoprotein; TG, triglyceride.
*
p value <0.05.
a
Patient number is far less than reference.