Table 1.

Affinity-based chromatin enrichment techniques used in epigenetic studies

Abbreviation	Alternative name	Method
ChIP-chip	ChIP-on-chip	Chromatin immunoprecipitation of DNA using epigenetic mark-specific antibodies, followed by the identification of the associated DNA using microarrays
ChIP-seq	ChIP-sequencing	Chromatin immunoprecipitation of DNA using epigenetic mark-specific antibodies, followed by the identification of the associated DNA using sequencing
MeDIP-seq	Methylated DNA immunoprecipitation	Immunoprecipitation of methylated DNA using methylated DNA-specific antibodies, followed by the identification of the associated DNA using sequencing
4C-seq/HiC-seq	Circular chromosome conformation capture-sequencing	Cross-linking of locally interacting DNA regions, followed by the identification of those DNAs using sequencing
ChIP-MS	ChIP-mass spectrometry	Chromatin immunoprecipitation of DNA using epigenetic mark-specific antibodies, followed by the identification of the associated proteins using mass spectrometry