Figure 4.

Inverse relationship of the MinD and MinE concentrations on oscillation frequency. (A) “Normal” pattern. (B) An increase of the MinE precursor production (σ_e from 0.002 to 0.004) leads to a higher oscillation frequency, because less time is required to remove MinD. (C) Conversely, a decrease (σ_e = 0.001) leads to a lower frequency (note that the MinE wave does not have to reach a pole before MinD can trigger at the opposite pole). (D) The lowering of MinD precursor synthesis (σ_d from 0.0035 to 0.002) leads to more rapid oscillations, because less MinD has to be removed from the membrane. All simulations start with identical initial situations.