. 2019 Apr 9;10:385. doi: 10.3389/fphys.2019.00385

Table 4.

False-positive report probability values for associations between recurrent miscarriage risk and genotypes of MALAT1 polymorphisms.

Genotype/allele	OR (95% CI)	P-value^a	Statistical power^b	Prior probability
				0.25	0.1	0.01	0.001	0.0001
MALAT1/rs619586 A > G
AG vs. AA	0.672 (0.459–0.984)	0.041	0.505	0.196	0.422	0.889	0.988	0.999
GG vs. AA	0.279 (0.080–0.978)	0.046	0.115	0.546	0.783	0.975	0.998	1.000
AG/GG vs. AA	0.623 (0.431–0.903)	0.012	0.358	0.091	0.232	0.769	0.971	0.997
G vs. A	0.619 (0.444–0.862)	0.005	0.346	0.042	0.115	0.589	0.935	0.993
AG/GG vs. AA
<35 years	0.534 (0.345–0.827)	0.005	0.171	0.081	0.208	0.743	0.967	0.997
2–3 abortions	0.585 (0.381–0.381)	0.014	0.277	0.132	0.313	0.834	0.981	0.998
Protective genotypes
0–1 vs. 2–3	0.373 (0.201–0.690)	0.002	0.064	0.086	0.219	0.755	0.969	0.997
<35 years	0.290 (0.142–0.589)	0.001	0.028	0.096	0.243	0.779	0.973	0.997
2–3 abortions	0.275 (0.128–0.589)	0.001	0.023	0.115	0.281	0.811	0.977	0.998

^aCalculated the genotype frequency distributions using the omnibus χ² test in Tables 2, 3. ^bCalculated the statistical power using the number of observations and the OR and P-values in Tables 2, 3. Statistically significant values are shown in bold (P < 0.05).