Table 2.
Effect of the intervention on syphilis screening and treatment rates at the first antenatal care visit
|
Intervention group |
Control group |
Absolute difference between median proportions (95% CI) | p value* | |||
|---|---|---|---|---|---|---|
| Women (n=18 357), n/N | Clinics (n=13), median proportion† (IQR) | Women (n=17 679), n/N | Clinics (n=13), median proportion† (IQR) | |||
| Primary outcomes | ||||||
| Women screened for syphilis | 18 314/18 357 | 99·9% (99·0 to 100·0) | 17 036/17 679 | 93·8% (85·0 to 98·9) | 6·1% (1·1 to 14·1) | 0·00092 |
| Women treated (proportion of those positive for syphilis)‡ | 889/894 | 100·0% (99·7 to 100·0) | 534/991 | 43·2% (2·6 to 83·2) | 56·8% (12·8 to 99·0) | 0·0028 |
| Secondary outcomes | ||||||
| Women screened for anaemia at their first clinic visit | 8666/18 357 | 50·0% (22·3 to 75·8) | 8097/17 679 | 57·0% (27·7 to 70·5) | −7·0% (−24·9 to 30·8) | 0·72 |
| Women screened for proteinuria at their first clinic visit | 2171/18 355 | 0·8% (0·3 to 7·2) | 1458/17 677 | 0·1% (0·0 to 1·8) | 0·7% (−0·2 to 6·3) | 0·22 |
| Women screened for HIV at their first clinic visit | 15 422/18 320 | 86·5% (78·1 to 90·5) | 14 189/17 678 | 81·1% (68·4 to 84·8) | 5·4% (−2·4 to 15·9) | 0·10 |
*
Wilcoxon rank sum test.
†
The clinic is the unit of analysis.
‡
For three clinics in the control group in the Democratic Republic of the Congo, the proportion of women screened positive for syphilis who were treated at the first visit could not be calculated because the clinic had no women who were positive for syphilis.