Table 3.

Results of group differences in diffusion parameters by regions of interest

		FA		MD		AD		RD
	Hemisphere	F	p	F	p	F	p	F	p
Superior longitudinal fasciculus	R	1.25	0.301	1.35	0.269	3.46	0.023†	0.76	0.520
	L	1.49	0.228	0.56	0.643	2.25	0.093	0.15	0.932
Superior fronto-occipital fasciculus	R	0.60	0.615	0.66	0.581	0.95	0.424	0.41	0.748
	L	0.05	0.987	0.27	0.844	0.27	0.847	0.26	0.856
Uncinate fasciculus	R	2.20	0.099	0.13	0.943	0.35	0.786	0.25	0.863
	L	1.61	0.197	1.26	0.296	1.35	0.268	1.21	0.317
Cerebellar peduncle
Inferior	R	1.26	0.299	2.94	0.042*	3.31	0.027*	2.74	0.053
	L	1.11	0.352	0.85	0.473	0.12	0.945	1.11	0.353
Middle		1.02	0.390	2.40	0.078	2.89	0.044*	2.12	0.109
Superior	R	1.28	0.292	0.38	0.770	0.90	0.449	0.41	0.746
	L	2.57	0.064	1.17	0.330	2.51	0.068	0.31	0.820
Corticospinal tract	R	2.43	0.076	3.05	0.037*	1.98	0.129	3.56	0.020*
	L	0.70	0.557	0.36	0.786	0.63	0.600	0.37	0.772
Cerebral peduncle	R	0.60	0.615	0.93	0.431	1.46	0.237	0.73	0.539
	L	0.38	0.769	0.73	0.539	1.23	0.309	0.56	0.647
Posterior thalamic radiation	R	0.84	0.478	0.63	0.599	1.00	0.402	0.48	0.699
	L	1.31	0.282	2.32	0.086	2.30	0.088	2.19	0.100
Fornix		3.32	0.027*	2.02	0.122	1.82	0.154	2.21	0.097
Cingulum	R	0.49	0.689	0.88	0.458	1.23	0.310	0.69	0.562
	L	0.05	0.985	0.95	0.423	1.25	0.301	0.80	0.497
Corpus callosum
Genu		1.32	0.278	1.29	0.289	1.34	0.273	1.25	0.302
Body		0.83	0.482	2.05	0.119	2.01	0.125	2.01	0.125
Splenium		0.78	0.511	1.79	0.160	1.98	0.129	1.61	0.198

AD, axial diffusivity; FA, fractional anisotropy; MD, mean diffusivity; RD, radial diffusivity.

Axial diffusivity was significantly lower in the right superior longitudinal fasciculus of alcohol-exposed infants compared to controls.

^*Post-hoc investigation of univariate tests of significance, revealed that age contributed significantly to the model.

^†Significant group difference at p< 0.05 after controlling for age and gender.