Table 5.
The HLA-G allele frequencies in the women with antiphospholipid syndrome (APS), preeclampsia (PE), intrauterine growth restriction (IUGR), recurrent spontaneous abortion (RSA), and their partners. The risk of APS, PE, IUGR, and RSA in these women and in the control group (C).
|
HLA-G
Allele |
APS vs. C | PE vs. C | ||||||||||
| Women | Men | Women | Men | |||||||||
| OR | (95% Cl) | p | OR | (95% Cl) | p | OR | (95% Cl) | p | OR | (95% Cl) | p | |
| 105N | 0.85 | 0.00–4.30 | 1.000 | 1.61 | 0.36–7.11 | 0.679 | 1.24 | 0.00–6.34 | 1.000 | 0.00 | 0.00–2.56 | 0.553 |
| 106 | 2.66 | 0.93–7.62 | 0.108 | 1.92 | 0.66–5.60 | 0.258 | 0.36 | 0.00–2.40 | 0.669 | 2.45 | 0.83–7.20 | 0.133 |
| 10101 | 0.50 | 0.38–0.93 | 0.03 | 0.77 | 0.48–1.25 | 0.327 | 0.87 | 0.53–1.34 | 0.613 | 0.85 | 0.51–1.42 | 0.598 |
| 10102 | 0.95 | 0.58–1.56 | 0.9 | 1.03 | 0.58–1.81 | 1.000 | 0.95 | 0.55–1.65 | 0.889 | 1.17 | 0.65–2.13 | 0.642 |
| 10103 | 0.80 | 0.31–2.06 | 0.808 | 0.65 | 0.23–1.82 | 0.608 | 0.66 | 0.22–2.03 | 0.586 | 0.32 | 0.00–1.30 | 0.152 |
| 10106 | 0.21 | 0.00–0.80 | 0.037 | 3.23 | 0.42– | 0.561 | 0.3 | 0.00–1.95 | 0.427 | 2.01 | 0.00– | 1.000 |
| 10108 | 3.24 | 1.16–9.05 | 0.042 | 0.88 | 0.30–2.58 | 1.000 | 5.91 | 2.13–16.29 | 0.001 | 2.12 | 0.83–5.39 | 0.128 |
| 10110 | 3.88 | 0.55– | 0.324 | 4.89 | 0.69– | 0.162 | 3.77 | 0.49– | 0.282 | 0.99 | 0.00– | 1.000 |
| 10401 | 1.92 | 0.81–4.53 | 0.182 | 0.88 | 0.30–2.58 | 1.000 | 0.4 | 0.00–1.68 | 0.339 | 0.88 | 0.28–2.88 | 1.000 |
|
HLA-G
Allele |
IUGR vs. C | RSA vs. C | ||||||||||
| Women | Men | Women | Men | |||||||||
| OR | (95% Cl) | p | OR | (95% Cl) | p | OR | (95% Cl) | p | OR | (95% Cl) | p | |
| 105N | 0.87 | 0.00–6.23 | 1.000 | 0.82 | 0.00–3.15 | 0.559 | 2.08 | 0.51–8.48 | 0.44 | 0.49 | 0.00–3.48 | 0.651 |
| 106 | 1.05 | 0.00–4.83 | 1 | 1.68 | 0.49–5.73 | 0.481 | 1.24 | 0.35–4.35 | 0.743 | 1.25 | 0.39–3.95 | 0.761 |
| 10101 | 1.44 | 0.82–2.52 | 0.254 | 0.83 | 0.48–1.45 | 0.572 | 1.19 | 0.74–1.89 | 0.551 | 0.84 | 0.53–1.35 | 0.548 |
| 10102 | 0.61 | 0.31–1.19 | 0.191 | 1.67 | 0.91–3.07 | 0.107 | 0.7 | 0.41–1.22 | 0.221 | 1.19 | 0.69–2.05 | 0.575 |
| 10103 | 0.95 | 0.31–2.94 | 1.000 | 0.6 | 0.18–2.04 | 0.564 | 0.68 | 0.24–1.94 | 0.604 | 0.99 | 0.40–2.44 | 1.000 |
| 10106 | 0.43 | 0.00–2.78 | 0.677 | 5.03 | 0.65– | 0.202 | 0.25 | 0.00–1.16 | 0.251 | 1.49 | 0.00– | 1.000 |
| 10108 | 2.16 | 0.61–7.70 | 0.266 | 0.53 | 0.00–2.26 | 0.518 | 2.56 | 0.86–7.64 | 0.144 | 0.82 | 0.28–2.39 | 0.787 |
| 10110 | 0.00 | 0.00– | 1.000 | 5.03 | 0.65– | 0.202 | 1.54 | 0.00–12.61 | 1.000 | 1.49 | 0.00– | 1.000 |
| 10401 | 0.57 | 0.00–2.41 | 0.732 | 0.26 | 0.00–1.01 | 0.063 | 0.85 | 0.29–2.48 | 1.000 | 1.16 | 0.44–3.11 | 0.797 |
Fisher’s two-sided exact test.