Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2018 Dec 26;28(9):1487–1497. doi: 10.1093/hmg/ddy440

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2018. Published by Oxford University Press.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.

PMC Copyright notice

In vivo functional enhancers in the ZEB2 locus. (A) UCSC Genome Browser (http://genome.ucsc.edu) tracks represent UCSC genes, H3K27ac ChIP-seq peaks of human interneuron progenitors, selected enhancer candidates and chrome ImputedHMM track from roadmap displays chromatin state segmentation for H1 and H9 ESC-derived neurons and human fetal brain (female and male). Black boxes represent enhancer candidates that were tested in zebrafish. Dashed rectangles represent positive enhancers in zebrafish. (B–J) Tissue-specific enhancers in zebrafish embryos at 24 and 48 hpf reflected by GFP expression in the (B) notochord (ZEB2#e2), (C) mid/hindbrain and spinal cord (ZEB2#e3), (D and E) notochord (ZEB2#e4 and 12), (F) mid/hindbrain and spinal cord (ZEB2#e5), (G and H) specific neurons with morphology-like trigeminal ganglia (ZEB2#e6 and 7) and (I) CNS (ZEB2#e14).