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. 2019 Mar 6;11(3):226. doi: 10.3390/v11030226

Table 1.

FUT2 polymorphisms with known effect on secretor status in different populations. Adapted from [31]. The two most common and investigated in genetic susceptibility studies are highlighted in bold.

Allele Mutation Type Phenotype Population
Se302 Missense Non-secretor a Thai, Bangladeshi
Se385 Missense Weak-secretor East Asian
Se428 Nonsense Non-secretor Caucasian, African, Meso-American, Central Asian
Se571 Nonsense Non-secretor Filipino and Samoan
Se628 Nonsense Non-secretor Japanese and Chinese
Se658 Nonsense Non-secretor Chinese
Se357,480,778 Frameshift Non-secretor African
Se849 Nonsense Non-secretor Chinese and Filipino
Sedel1 Deletion Non-secretor Indian and Bangladeshi
Sedel2 Deletion Non-secretor Samoan
Sefus Fusion Weak-secretor Japanese

a No α1,2-fucosyltransferase activity found in transfected COS7 cells [32].