Table 2.
mAb | Type | Reactivity | ELISA (Irradiated Virus) |
Western Blot (Irradiated Virus) |
Confocal Microscopy (Wild-Type Infection) |
---|---|---|---|---|---|
15D10 | IgG1 | EBOV | ++ | ++ | ++ |
6E5 | IgG1 | ++ | ++ | ++ | |
3F12 | IgG1 | SUDV | ++ | +++ | + |
11G9 | IgG1 | +++ | +++ | ++ | |
6G5 | IgG1 | ++ | +++ | ++ | |
12F12 | IgG1 | +++ | + | ++ | |
2A10 | IgG1 | RESTV | ++ | ++ | ++ |
7E7 | IgG1 | ++ | ++ | ++ | |
4B10 | IgG2b | TAFV | ++ | +++ | + |
2A10 | IgG1 | ++ | +++ | + | |
8G9 | IgG1 | ++ | +++ | − | |
1H3 | IgG1 | ++ | +++ | +++ | |
3E10 | IgM | MARV | ++ | +++ | +/− |
6E9 | IgG2b | +++ | +++ | ++ | |
5E9 | IgM | + | +++ | + | |
8H4 | IgG1 | +++ | +++ | +++ | |
7A12 | IgG1 | +++ | +++ | +++ | |
1G10 | IgG1 | + | + | − | |
2G10 | IgG1 | EBOV | +++ | +++ | +++ |
SUDV | ++ | + | ++ | ||
TAFV | ++ | + | ++ | ||
RESTV | + | − | +++ | ||
MARV | − | − | − | ||
BDBV | ++ | +++ | ND | ||
4F9 | IgM | EBOV | +++ | +++ | +++ |
SUDV | +++ | + | ++ | ||
TAFV | ++ | + | ND | ||
RESTV | + | − | +++ | ||
MARV | − | − | + | ||
BDBV | ++ | +++ | ND |
+++ Highly reactive, ++ Moderately Reactive, + Weakly reactive, − non-reactive, ND not done.