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X-ray crystal structures of NS5B GT 1b 316N bound with (a) benzyl boronic acid 1 (PDB ID 4KAI); (b) oxazolidinone 25 (PDB ID 6MVK); (c) triazole 31 (PDB ID 6MVQ); and (d) N-phenyl 45 (PDB ID 6MVP). Highlighted are interactions with Arg200 and Tyr448 [residues labeled in panel (a) only for clarity].
