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. 2019 Jan 28;10(4):437–443. doi: 10.1021/acsmedchemlett.8b00484

Table 2. Inhibitory Effect of Compounds 1, 2, and INDO on Cell Proliferation.

cmpd LNCaP IC50 ± SEM (μM) VCaP IC50 ± SEM (μM) HCT 116 IC50 ± SEM (μM) HT-29 IC50 ± SEM (μM)
INDO 238.4 ± 1.1 136.9 ± 1.0 136.8 ± 1.0 312.6 ± 1.1
1 141.2 ± 1.0b 138.1 ± 1.2 78.9 ± 1.2 134.7 ± 1.2a
2 116.6 ± 1.1c 69.1 ± 1.0d,e 110.7 ± 1.2 82.0  ± 1.2b
a

p < 0.05.

b

p < 0.01.

c

p < 0.001.

d

p < 0.0001 compound 1 or 2 vs INDO.

e

p < 0.0001 compound 2 vs 1.