. 2019 Jan 28;10(4):511–516. doi: 10.1021/acsmedchemlett.8b00536

Table 2. Antiproliferative Activity of the Enantiomers (R)-1 and (S)-1 in siNMDA R MCF-7 and SKBR3 Cell Lines, Compared with Untransfected Cells^a.

	GI₅₀ (μM)
cell line	(R)-1	(S)-1
MCF-7 untrasfected	250 ± 6.5	99 ± 3.5
MCF-7 siNMDA R	210 ± 2.3	520 ± 8.7
SKBR3 untrasfected	74 ± 4.8	23 ± 2.8
SKBR3 siNMDA R	66 ± 1.9	57 ± 1.3

Cells were treated for 48 h with different doses of (R)-1 and (S)-1. Cell viability was determined by SRB assay. Data are expressed as mean ± SE of three separate experiments.

Table 2. Antiproliferative Activity of the Enantiomers (R)-1 and (S)-1 in siNMDA R MCF-7 and SKBR3 Cell Lines, Compared with Untransfected Cellsa.

Table 2. Antiproliferative Activity of the Enantiomers (R)-1 and (S)-1 in siNMDA R MCF-7 and SKBR3 Cell Lines, Compared with Untransfected Cells^a.