Effects of gamma-tocotrienol (GT3) pretreatment on total body irradiation (TBI)-induced intestinal damage. Representative photomicrograph of TUNEL-positive cells (green) in (A) vehicle (veh) un-irradiated, (B) GT3 un-irradiated, (C) vehicle irradiated, and (D) GT3 irradiated groups. (E) Frequency of TUNEL-positive cells in the intestine of sham-irradiated or irradiated mice, with or without GT3 pretreatment, TUNEL-positive cells were counted 24 h after 8 Gy TBI; (F) Villus height measured 4 d after 8 Gy TBI in sham-irradiated or irradiated groups, with or without GT3 pretreatment; (G) Crypt depth measured 4 d after 8 Gy TBI in sham-irradiated or irradiated groups, with or without GT3 pretreatment. Data represent the mean ± standard error of the mean (SEM). NS = not significant.