Table 3.

MLV Insertions

Mutation	MGI IDa	Strain of origin	ERV location, orientationb	Mutational mechanisms or effects	References
Abcb1a mds	3044239	CF-1	Solitary MLV LTR, Intron 22, −	Transcripts contain viral sequence, Exon skipping, Disruption of gene function.	[258, 259]
Aifm1 Hq	1861097	CF-1	Intron 1, +	80% decrease in transcript and protein levels, Aberrant splicing	[260]
Hr hr	1856057	HRS/J	Intron 6, +	Transcripts contain viral sequence, Probable termination within LTR	[24, 137]
Lamc2 jeb	3609880	129X1/SvJ	Solitary MLV LTR, intron 18, +	Aberrant splicing and premature termination, low level of normal transcripts	[261]
Lmf1 cld	1856820	M. m. musculus	Intron 7,?	Transcripts contain ERV sequence, Termination within ERV	[262]
Myo5a d	1856004	Fancy mice	Intron, +	Shortened and abnormally spliced transcripts that vary among tissues	[135]
Pde6b rd1	1856373	unknown	Intron 1, −	Associated with nonsense mutation in gene but effect of ERV is unclear	[263]

^aID number in Mouse Genome Informatics (MGI) database

^b- = antisense, + = sense,? = orientation unknown