1.2. Analysis.
Comparison 1 Influenza immunity in vaccinated children receiving chemotherapy compared with vaccinated children not receiving chemotherapy, Outcome 2 Number of participants with four‐fold rise in antibody titre after last immunisation.
| Number of participants with four‐fold rise in antibody titre after last immunisation | ||||||
|---|---|---|---|---|---|---|
| Study | Influenza strain | On chemotherapy n% | On chemotherapy Total N | Off chemotherapy n% | Off chemotherapy Total N | P‐value |
| Chisholm 2005 | A/NC/20/99 | 30 (53%) | 56 | 4 (44%) | 9 | 0.13 |
| Chisholm 2005 | A/PAN/2007/99 | 19 (34%) | 56 | 3 (33%') | 9 | 0.85 |
| Chisholm 2005 | B/Sichuan 379 99 | 28 (50%) | 56 | 5 (55%) | 9 | 0.86 |
| Matsuzaki 2005 | A/NC/20/99 | 6 (38%) | 16 | 20 (83%) | 24 | 0.004 |
| Matsuzaki 2005 | A/PAN/2007/99 | 4 (25%) | 16 | 12 (50%) | 24 | 0.105 |
| Matsuzaki 2005 | B/Shan/7/97 | 6 (33%) | 18 | 14 (54%) | 26 | 0.227 |
| Steinherz 1980 | A/NJ/76 | 19 (38%) | 50 | 16 (76%) | 21 | < 0.01 |
| Steinherz 1980 | A/Vic/75 | 26 (52%) | 50 | 18 (86%) | 21 | < 0.05 |
| Steinherz 1980 | ||||||