2.1. Analysis.
Comparison 2 Influenza immunity in vaccinated children receiving chemotherapy compared with vaccinated healthy children, Outcome 1 Number of participants with four‐fold rise in antibody titre after last immunisation.
| Number of participants with four‐fold rise in antibody titre after last immunisation | ||||||
|---|---|---|---|---|---|---|
| Study | Influenza strain | On chemotherapy n% |
On chemotherapy Total N |
Healthy n% |
Healthy Total N |
P‐value |
| Porter 2004 | A/NC/20/99 | 13 (65%) | 20 | 41 (89%) | 46 | P = 0.034 |
| Porter 2004 | A/PAN/2007/99 | 13 (65%) | 20 | 36 (78%) | 46 | P = 0.258 |
| Porter 2004 | B/Vic/504/2000 | 12 (60%) | 20 | 35 (76%) | 46 | P = 0.185 |
| Shahgholi 2010 | A/SI 3/2006 | 18 (56,2%) | 32 | 24 (80%) | 30 | P = 0.04 |
| Shahgholi 2010 | A/Wis/67/2005 | 13 (40,6%) | 32 | 16 (53,3%) | 30 | P = 0.31 |
| Shahgholi 2010 | B/Mal/2506/2004 | 19 (59,4%) | 32 | 25 (83,3%) | 30 | P = 0.038 |
| Steinherz 1980 | A/NJ/76 | 19 (38%) | 50 | 5 (71%) | 7 | P = 0.204 |
| Steinherz 1980 | A/Vic/75 | 26 (52%) | 50 | 6 (86%) | 7 | P = 0.202 |
| Steinherz 1980 | ||||||