2.2. Analysis.
Comparison 2 Influenza immunity in vaccinated children receiving chemotherapy compared with vaccinated healthy children, Outcome 2 Geometric mean titre (GMTs) pre‐ and post‐vaccination.
| Geometric mean titre (GMTs) pre‐ and post‐vaccination | ||||||
|---|---|---|---|---|---|---|
| Study | Influenza strain | On chemotherapy GMT pre‐vaccination | On chemotherapy GMT post‐vaccination | Healthy GMT pre‐vaccination | Healthy GMT post‐vaccination | P‐value |
| Lange 1979 | A/NJ/76 | <8 ± 0.00 | 37.74 ± 1.28 | <8 ± 0.00 | 52.39 ± 1.13 | 0.53 |
| Lange 1979 | A/Vic/75 | 10.62 ± 1.14 | 61.92 ±1.26 | 12.51 ±1.12 | 70.34 ± 1.12 | 0.80 |
| Lange 1979 | ||||||
| Porter 2004 | A/NC/20/99 | 6.50 | 53.82 | 15.06 | 367.03 | < 0.001 |
| Porter 2004 | A/Pan/2007/99 | 29.86 | 152.22 | 72.20 | 577.59 | < 0.03 |
| Porter 2004 | B/Vic/504/2000 | 8.57 | 39.4 | 13.15 | 165.37 | < 0.003 |
| Shahgholi 2010 | A/SI 3/2006 | 32,5 | 52,87 | 31,5 | 76,38 | 0,13 |
| Shahgholi 2010 | A/Wis/67/2005 | 54 | 81,87 | 54 | 145,41 | 0.04 |
| Shahgholi 2010 | B/Mal/2506/2004 | 12,8 | 25,41 | 17 | 38.07 | 0.10 |