Hsieh 2002b.

Methods	CCT conducted in Taiwan during the 2000‐2001 influenza season Response to influenza vaccine in children with ALL is compared with that of children with asthma
Participants	30 children with asthma in remission (no inhaled steroids within 2 weeks or oral steroids within 1 month before influenza vaccination), mean age 6.5 years, compared with 25 children with ALL receiving maintenance chemotherapy, mean age 7.3 years
Interventions	Trivalent inactivated split virus (Vaxigrip) influenza vaccine A/Panama/2007/99 (H3N2), A/New Caledonis/20/99 (H1N1), B/Yamanashi/166/98. Participants received two 0.5 ml doses containing 15 µg hemagglutinin, 4 weeks apart
Outcomes	(1) GMT pre‐ and post‐vaccination (2) Development of protective HI titre (≥ 40) post‐vaccination (3) Four‐fold rise in antibody titre after vaccination (4) Adverse reactions
Notes	Dosage: > 8 years received 1 dose, and children younger than 8 received two doses of vaccine