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. 2019 Apr 16;10:29. doi: 10.1186/s40104-019-0336-7

Table 7.

Expression of toll-like receptor signaling pathway genes in fetal Xiangdong black goats liver during the pregnancy

Item Control group Restriction group SEM P treatment P sex P treatment × sex
MyD88-dependent
 TLR2 1.11 1.74 0.161 0.001 0.104 0.160
 TLR4 1.06 1.34 0.094 0.003 0.128 0.025
 TLR7 1.12 1.06 0.090 0.410 0.510. 0.006
 MyD88 1.06 1.61 0.099 < 0.001 0.053 0.642
 IRAK1 1.05 1.28 0.096 0.356 0.273 0.029
 TRAF6 1.06 1.32 0.093 0.005 0.274 0.282
 IRF7 1.14 1.18 0.117 0.697 0.645 0.161
 NFKB1 1.08 1.33 0.094 0.008 0.636 0.027
 NFKBIA 1.03 1.25 0.045 < 0.001 0.797 0.148
MyD88-independent
 TLR3 1.06 1.15 0.070 0.099 0.671 0.071
 TRIF 1.04 1.24 0.079 0.101 0.082 0.451
 TBK1 1.05 1.22 0.096 0.106 0.396 0.789
 IRF3 1.10 1.36 0.085 0.111 0.402 0.543
Cytokine
 IFN-β 1.08 1.32 0.088 0.034 0.207 0.689
 TGF-β 1.04 1.26 0.106 0.019 0.469 0.093
 TNF-α 1.00 1.95 0.361 < 0.001 0.004 0.001
 IL-1β 1.05 1.36 0.086 < 0.001 0.133 <  0.001