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Comparison of malaria chemoprophylaxis options
| Agent | Mefloquine | Doxycycline | Atovoquone-proquanil | Primaquine | Tafenoquine |
|---|---|---|---|---|---|
| Dosing | Weekly | Daily | Daily | Daily | Weekly |
| Radical cure | No | No | No | Yes | Yes |
| P. falciparum active | Yes | Yes | Yes | Yes | Yes |
| Pregnancy | Yes | No | No | No | No |
| G6PD safety | Yes | Yes | Yes | No | No |
| Children | Yes | No | Yes | Yes | ? |
| Resistance | Yes | Yes | Yes | No | Unlikely |
| CYP dependent | No | No | No | Yes | ? |
