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| Trial type / duration | Sample size | Regions / species | Placebo | Efficacy |
|---|---|---|---|---|
| RCT/6 months [81] | 615 soldiers | Timor / Australia P. falciparum and P. vivax |
No | N/A – 4 cases in TQ arm |
| RCT/15 weeks [82] | 123 Adults | Kenya P. falciparum |
Yes | 86% |
| RCT/12 weeks [83] | 231 Adults | Ghana P. falciparum |
Yes | 87% (equivalent to mefloquine) |
| Experimental exposure to P. falciparum [84]. | 16 Adults (4 controls) | Australia P. falciparum |
Yes | 100% |
