Table 2.
Overall and cause-specific standardised mortality ratios (SMRs) by age at diagnosis.
| Age at diagnosis |
|||||||||
|---|---|---|---|---|---|---|---|---|---|
| <15 years
(n = 284) |
≥15 years
(n = 318) |
Overall (n = 602) |
|||||||
| Cause of death | Obs | Exp | SMR (95% CI) | Obs | Exp | SMR (95% CI) | Obs | Exp | SMR (95% CI) |
| All cause | 32 | 15.20 | 2.11 (1.44–2.97)a | 205 | 151.02 | 1.36 (1.18–1.56)a | 237 | 166.22 | 1.43 (1.25 – 1.62)a |
| All malignancy | 8 | 3.74 | 2.14 (0.92–4.21) | 50 | 41.57 | 1.20 (0.89–1.59) | 58 | 45.32 | 1.28 (0.97–1.65) |
| Digestive cancer | <5 | b | 0.00 (0.00–4.53) | 16 | 10.82 | 1.48 (0.85–2.40) | 16 | 11.63 | 1.38 (0.79–2.23) |
| Lymphatic and haematopoietic tissue malignancy | <5 | b | 8.03 (1.66–23)a | 13 | 2.73 | 4.77 (2.54–8.16)a | 16 | 3.1 | 5.16 (2.95–8.38)a |
| Breast cancer | <5 | b | 2.69 (0.07–15) | <5 | b | 0.00 (0.00–2.76) | <5 | b | 0.59 (0.01–3.26) |
| Cerebrovascular disease | <5 | b | 4.42 (0.53–16) | 25 | 19.43 | 1.29 (0.83–1.90) | 27 | 19.88 | 1.36 (0.90–1.98) |
| Ischaemic heart disease | <5 | b | 0.00 (0.00–2.86) | 42 | 35.63 | 1.18 (0.85–1.59) | 42 | 36.92 | 1.14 (0.82–1.54) |
| Accident, suicide and violence | 7 | 2.67 | 2.62 (1.05–5.40)a | <5 | b | 0.90 (0.24–2.30) | 11 | 7.13 | 1.54 (0.77–2.76) |
CI: confidence interval; Exp: expected deaths; Obs: observed deaths.
a
p < 0.05; bIn order to minimise the risk of disclosure of the identity of individual study participants, we have adhered to the rule of thumb suggested by the Office for National Statistics of suppressing all cell frequencies where the observed cell frequency is less than 5 (‘Review of the Dissemination of Health Statistics: Confidentiality Guidance: National Statistics; HMSO 2006’).