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. 2019 Apr 15;17:34. doi: 10.1186/s12964-019-0346-2

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 5 — Sex differences in basal mRNA expression of PLB, SLN, SERCA2a, and RyR2 are modulated by E2. GAPDH levels were similar in all groups (a) Relative RyR2 mRNA levels normalized to GAPDH mRNA in sham, male, OVX, and OVX + E2. (n = 3 mice). b Relative SERCA2a mRNA levels normalized to GAPDH mRNA in sham, male, OVX, and OVX + E2. (n = 3 mice). c Relative PLB and SLN mRNA levels normalized to GAPDH mRNA in sham, male, OVX, and OVX + E2. (n = 3 mice). ^*P < 0.05, ^**P < 0.01, and ^***P < 0.001. All data are presented as mean ± S.E.M