Fig. 8.

Estrogen compensates for the loss of function resulting from β₂AR-gene knockout in female LV apical myocytes. a current-voltage comparisons among Wt sham, Wt male, OVX, and OVX + E2 myocytes. (n = 6–10 cells/4 mice). b Effect of β₂AR on mRNA expression of the L-type Ca²⁺ channel depends on the E2 environment. (n = 3 mice). c Influence of E2 on β₂AR mRNA level. (n = 3 mice). ^*P < 0.05, ^**P < 0.01, ^***P < 0.001. All data are presented as mean ± S.E.M