Table 2.

Regression coefficient of the final model

	MCI/dementia				MCI/AD-dementia
	Coëfficient	Standard error	p value	Harrell’s C	Coëfficient	Standard Error	p value	Harrell’s C
Demographic (n = 481)
Age	0.0854	0.0147	< .001	0.70	0.0904	0.0162	< .001	0.70
MMSE	− 0.2497	0.0639	< .001		− 0.2236	0.0726	< .01
CSF (n = 344)
Aβ	− 1.0462	0.3668	< .01	0.82	− 1.3941	0.4031	< .01	0.84
Tau	1.2785	0.3384	< .001		1.3829	0.4003	< .01
Age	0.0704	0.0251	< .01		0.0644	0.0296	< .05
Gender	− 0.6360	0.3345	< .10		− 0.6375	0.3814	< .10
MMSE	− 0.25503	0.0815	< .01		− 0.1846	0.0981	< .10
Tau* age	− 0.1393	0.0467	< .01		− 0.1311	0.0534	< .05

CSF biomarkers (Aβ and Tau) are log-transformed and centered. MMSE mini-mental state examination, Tau* age interaction between age and Tau. Interaction term was centered and standardized to allow inclusion in the model